IMMUNE-RELATED GENETIC OVERLAP BETWEEN REGIONAL GRAY MATTER REDUCTIONS AND PSYCHIATRIC SYMPTOMS IN ADOLESCENTS, AND GENE-SET VALIDATION IN A TRANSLATIONAL MODEL

Adolescence is a period of vulnerability for the maturation of gray matter (GM) and also for the onset of psychiatric disorders such as major depressive disorder (MDD), bipolar disorder and schizophrenia.Chronic neuroinflammation is considered to play a role in the etiology of these illnesses.However, the involvement of neuroinflammation in the obs

Little Girls Tees In Primary Myelofibrosis (PMF), megakaryocyte dysplasia/hyperplasia determines the release of inflammatory cytokines that, in turn, stimulate stromal cells and induce bone marrow fibrosis.The pathogenic mechanism and the cells responsible for progression to bone marrow fibrosis in PMF are not completely understood.This review arti

Aim To determine whether serum testosterone levels predict hospitalised acute exacerbations of COPD (H-AECOPD), cardiovascular disease outcome, and mortality in people with COPD.Methods Separate analyses were carried out on two observational, multicentre COPD cohorts, Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (EC